Nuclear ReceptorsNur77andNurr1Modulate Mesenchymal Stromal Cell Migration
نویسندگان
چکیده
منابع مشابه
Mechanisms of mesenchymal stromal cell immunomodulation.
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years, the initial observations that MSCs could enhance regeneration and modulate immune responses have been significantly advanced and we now have a clearer picture of the effects that MSCs have on the immune system partic...
متن کاملKindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells
Kindlin-2 is a multidomain intracellular protein that can be recruited to β-integrin domains to activate signaling, initiate transcriptional programs, and bind to E-cadherin. To explore its involvement in cell fate decisions in mesenchymal cells, we studied the effects of Kindlin-2 modification (overexpression/knockdown) in induced pluripotent cell-derived mesenchymal stromal cells (iPSC-MSCs)....
متن کاملP-58: Mesenchymal Stromal Cell Cultures from Human Testis Tissue Cryopreservation and Their Potential for The Future Cell Therapy Applications
N;
متن کاملThe Level of Mesenchymal-Epithelial Transition Autophosphorylation is Correlated with Esophageal Squamous Cell Carcinoma Migration
Background: The MET receptor is a critical member of cancer-associated RTKs and plays an important role in different biological activities, including differentiation, migration, and cell proliferation. Methods: In this study, novel MET inhibitors were introduced and applied on esophageal squamous carcinoma cell line KYSE-30, and the level of proliferation and migration, as well as the activated...
متن کاملEpithelial to mesenchymal transitions and cell migration
Epithelial to mesenchymal transitions are prominent features of mammalian gastrulation and neural crest development, and are essential for the proper development of many organs and tissues. Moreover, most cancers derive from epithelial cells, and metastasis involves departure of these cells from their epithelium of origin and invasion of the surrounding tissue. It is known that epithelial to me...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stem Cells and Development
سال: 2012
ISSN: 1547-3287,1557-8534
DOI: 10.1089/scd.2011.0076